GREEN BAY, Wis. -- Packers sack leader Nick Perry could be done for the season after he sustained what coach Mike McCarthy called "significant hand injury."
Combine that with Clay Matthews' lingering shoulder injury, and the Packers pass rush may be significantly impacted in a key NFC game Sunday against the Seattle Seahawks at Lambeau Field.
Perry, who was injured in the first half of the game Sunday against the Houston Texans, tried to play in the second half with a large cast on his left hand but lasted only a couple of plays.
A source said Perry had surgery on the hand.
McCarthy said Perry would be re-evaluated next week to see if he could return this season.
"I don't know the specifics of how long they think it's going to be, but I know talking with Nick, he wants to go," McCarthy said Wednesday. "So that's why we're going to look at it Monday, and see where he is."
It assures that Perry, the Packers' first-round pick in 2012, will fail to play in all 16 games for the fifth time in as many NFL seasons. To this point, Perry had been off to his best start with a career-high eight sacks. Perry was playing on a one-year, $5 million contract after the Packers declined to pick up the fifth-year option his rookie deal.
"I feel terrible for Nick," McCarthy said. "He was having a great season, clearly his best season. He's had a setback. How we plan moving forward, frankly it's the same thing we do each and every week. It's based on the health of your team. Our job is to put players in position to be successful. We feel good about our plan, and plan on being successful Sunday."
Matthews won't practice on Wednesday or Thursday in an effort to help him be more effective than he was in a 29-snap stint against the Texans. He failed to record a single tackle or quarterback hit. Matthews suffered a separated AC joint in his left shoulder on what he called a "cheap-shot" block by Philadelphia Eagles lineman Allen Barbre.
"He was extremely limited in the game," McCarthy said. "Each week it's going to get better. That's the hope. As far as having a setback, it didn't help him playing in the game. But I think it speaks volumes about Clay in gutting it out and so forth. ... We'll get to Saturday and kind of see where we are. But the goal is to try to get some strength back in the shoulder."
Also, McCarthy said quarterback Aaron Rodgers will be limited in practice for the second straight week because of the hamstring injury he sustained against the Eagles.
"Aaron will be limited today and then we'll see where he is tomorrow," McCarthy said. "He'll do probably very similar to what he did last week on Wednesday."