Here are the betting lines for every Friday first-round game from the Westgate Las Vegas SuperBook, besides the winners of the First Four games to be played Tuesday and Wednesday night.
For help with every selection, be sure to check out PickCenter, which has projections for every NCAA tournament game.
Lines as of Friday at 9:30 ET.
South Region
No. 1 North Carolina Tar Heels (-26.5) vs.
No. 16 Texas Southern Tigers
No. 8 Arkansas Razorbacks (PK) vs.
No. 9 Seton Hall Pirates
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No. 6 Cincinnati Bearcats (-4) vs.
No. 11 Kansas State Wildcats
No. 3 UCLA Bruins (-18) vs.
No. 14 Kent State Golden Flashes
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No. 7 Dayton Flyers vs.
No. 10 Wichita State Shockers (-6.5)
No. 2 Kentucky Wildcats (-20) vs.
No. 15 Northern Kentucky Norse
East Region
No. 3 Baylor Bears (-12.5) vs.
No. 14 New Mexico State Aggies
No. 6 SMU Mustangs (-6.5) vs.
No. 11 USC Trojans
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No. 7 South Carolina Gamecocks (-1.5) vs.
No. 10 Marquette Golden Eagles
No. 2 Duke Blue Devils (-19.5) vs.
No. 15 Troy Trojans
Midwest Region
No. 1 Kansas Jayhawks (-24) vs.
No. 16 UC Davis Aggies
No. 8 Miami (FL) Hurricanes (-2.5) vs.
No. 9 Michigan State Spartans
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No. 3 Oregon Ducks (-15) vs.
No. 14 Iona Gaels
No. 6 Creighton Bluejays (PK) vs.
No. 11 Rhode Island Rams
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No. 7 Michigan Wolverines (-2.5) vs.
No. 10 Oklahoma State Cowboys
No. 2 Louisville Cardinals (-19.5) vs.
No. 15 Jacksonville State Gamecocks