The RFU has announced that Rob Andrew will step down from his role as the RFU's director of professional rugby at the end of the season, with Nigel Melville coming on board in his place but with a wider remit.
Andrew's resignation was confirmed on Friday after the former England fly-half "instigated discussions" with RFU chief executive Ian Ritchie.
He has agreed to continue working on the latest agreement with Premiership Rugby, which will run until the end of the 2023 Rugby World Cup.
USA Rugby CEO Melville will arrive at Twickenham in the summer, assuming Andrew's role but also taking on the work previously done by head of international player development, Joe Lydon, who announced he would be leaving the RFU in March.
"We are delighted to welcome Nigel to the RFU in what is an exciting time for England Rugby for both the men's and women's games," Ritchie said.
"He will bring a great deal of expertise from not only his experiences from working in England but internationally at USA Rugby."
Melville said: "I would like to thank USA Rugby for their support and I am very proud of what has been achieved in the organisation and the game in the US over the last decade.
"However, I am now hugely excited about this opportunity to join England Rugby in what is a very buoyant time."
Andrew, meanwhile, said he was proud of the work he had done since joining the RFU in 2006, but felt it was time to step aside.
"After 10 years at the RFU and with the impending conclusion of the second Heads of Agreement, it feels like the right time to step down at the end of the season," he said.
"My role has primarily been to set up a structure that would ultimately deliver long-term success to England through a pipeline of talented players coming through the academy system.
"Bringing together the clubs to support the new academy scheme required recognition from the RFU to reward them to bring on successful academy players and I believe we have achieved this.
"The staff and coaches who have delivered this at both club and England junior level are the unsung heroes and I would like to give them the thanks and recognition they deserve.
"The pipeline is going from strength-to-strength and I believe will deliver Eddie Jones and his coaches the world-class players that England need to ensure increasing success going forward."