MOSCOW -- Top-seeded Kristina Mladenovic and No. 2 CoCo Vandeweghe lost their opening matches Wednesday at the Kremlin Cup.
Mladenovic landed only 49 percent of her first serves and lost to Aliaksandra Sasnovich 6-2, 2-6, 6-2. Vandeweghe fell to Lesya Tsurenko 7-5, 1-6, 6-2.
Mladenovic and Vandeweghe had received byes to the second round.
Fourth-seeded Anastasija Sevastova also lost, 6-4, 6-3 to Irina-Camelia Begu.
The upsets mean the highest-ranked player left in the tournament is No. 19 Elena Vesnina, who plays Natalia Vikhlyantseva later Wednesday.