LONDON -- Of the top 10 seeded players at Wimbledon, only one remains entering the round of 16 -- and it isn't No. 1.
Top-seeded Simona Halep was derailed by unseeded Su-Wei Hsieh 3-6, 6-4, 7-5 on Saturday, leaving No. 7 Karolina Pliskova as the only top-10 seed standing entering the second week of play at the Grand Slam event -- the fewest in a Grand Slam event in the Open era. For the first time in Wimbledon history, none of the top five women's seeds reached the round of 16.
Halep served for the match at 5-3 in the final set and had a match point in the next game, but the French Open champion couldn't capitalize on her chances.
"I had 5-2 in the third set. I had match point," Halep said. "Just didn't go my way today. She deserved to win."
Hsieh saved the match point with a backhand winner before holding for 5-5 and breaking Halep in the next game. The Romanian had two break points at 6-5 but couldn't take advantage.
"I knew she [was] going to fight really hard," Hsieh said. "So I know I need to be stronger than normal in mental [game]. I doing good today ...
"For me, I just try to enjoy the tennis, enjoy the city, enjoy the food. I feel I'm really lucky to be a tennis player, stay here until the second week. I'm very, very grateful and thankful for about all this."
The match featured 14 breaks of serve -- seven for each player -- including five straight to open the first set.
In addition to knocking off Halep here, Hsieh has also upset Garbine Muguruza at the Australian Open and Johanna Konta at the French Open.
"I don't learn how to be giant-killer," Hsieh said. "I just want to feel free and enjoy the match. You know anything can happen on the court. You don't have big chance to win, because they're very good. So all I want to do is just go on the court and hit the shot and run every point and enjoy it."
Halep is the first No. 1 seed to fail to reach the round of 16 at Wimbledon since Serena Williams in 2014. Halep entered the match looking to set the record for most career Grand Slam wins by a Romanian woman but instead will have to wait until the US Open to break her tie at 73 with Virginia Ruzici.
"I just believe that I was not very positive on court," Halep said. "The match was very unprofessional for me. But I am too tired. I was too tired. I have pain everywhere.
"I will not find the excuses about this match, she deserved to win, but still I'm sad about myself today."
Former finalist Angelique Kerber advanced to the fourth round at Wimbledon without facing a break point after beating 18th-seeded Naomi Osaka 6-2, 6-4.
Kerber, a two-time Grand Slam champion, who was runner-up to Williams here in 2016, hit 23 winners and made just five unforced errors against her Japanese opponent.
As well as being one of only two former finalists -- along with Williams -- to make it through to the fourth round, the 11th-seeded Kerber is the second highest seed remaining in the women's draw.
Kerber of Germany will next face 56th-ranked Belinda Bencic of Switzerland.
The Associated Press and ESPN Stats & Information contributed to this report.