Sale Sharks have enlisted Faf de Klerk and James O'Connor to help their search for a "world-class" lock and centre after Josh Beaumont joined Johnny Leota and Will Addison on the sidelines.
Director of rugby Steve Diamond confirmed Tuesday that second row Beaumont would miss three months of the season with a snapped bicep tendon sustained in Friday's defeat to Harlequins.
Sharks captain Addison has not played since limping out of the round three meeting with London Irish, while fellow centre Leota is yet to make it onto the pitch this term.
"With Josh getting injured we're out in the market for a world-class lock and with Johnny Leota and Will Addison out we are also in the market for a world-class centre," Diamond said.
"The message has gone out to agents that whether it is a short-term deal for three months or a long-term agreement for three years we are actively in the market for players in those two positions.
"Both Faf De Klerk and James O'Connor are assisting us in that search as they know people in South Africa and Australia respectively and they know of people in the Super Rugby fraternity who we may have missed out.
"So they are helping out at the minute trying to find those players for us."
On Beaumont's injury, Diamond said: "It is a blow as Josh had been playing really well and had adapted brilliantly to playing in the second row.
"He's had a few injury setbacks but he's only 23 and he's still a young lad. He's getting all the support he needs from us and all the support he needs from his family and I'm sure that he will come back bigger and stronger."