INDIANAPOLIS -- Buffalo Bills running back LeSean McCoy is in the concussion protocol after leaving Sunday's game against the Indianapolis Colts in the first quarter with a head injury and not returning.
Because of his injury, McCoy was not made available to reporters after the game.
McCoy fell hard on his helmet after running toward the sideline on a 1-yard rush. He later walked to the sideline under his own power before being evaluated in the sideline medical tent and then in the locker room. McCoy had two carries for 1 yard before being injured. He was replaced by Chris Ivory, who gained a season-high 21 yards on a second-quarter run. Ivory finished with 16 carries for 81 yards as well as three catches for 25 yards.
Sunday's game was the second this season that McCoy did not finish because of injury. He suffered cracked rib cartilage during a Week 2 loss to the Los Angeles Chargers and missed the Bills' next game at Minnesota.
The Bills will host the New England Patriots next week on Monday night. In addition to Ivory, the Bills have Marcus Murphy and Taiwan Jones on their roster at running back.
Quarterback Derek Anderson, who started Sunday's game less than two weeks after being signed by the Bills, was seen limping through the locker room after the game. Anderson said he got a "little banged up," although he finished the contest.
"I don't feel great right now," Anderson said. "I'm not gonna lie to you."