Star strikers Luis Suarez and Edinson Cavani headline Uruguay's 26-man preliminary World Cup squad named by Oscar Tabarez on Tuesday.
Major League Soccer's Nicolas Lodeiro, 29, has also received a call-up, while Sampdoria's Lucas Torreira leads a six-man contingent selected from Serie A.
Uruguay finished second in the CONMEBOL qualifiers and will face hosts Russia, Saudi Arabia and Egypt in Group A.
The final 23-man squads are due to FIFA by June 4, with La Celeste opening up their World Cup campaign against Mohamed Salah and Co. on June 15.
Uruguay's 26-man provisional World Cup squad:
Goalkeepers: Fernando Muslera (Galatasaray), Martin Silva (Vasco da Gama), Martin Campana (Independiente)
Defenders: Diego Godin (Atletico Madrid), Sebastian Coates (Sporting CP), Jose Maria Gimenez (Atletico Madrid), Maximiliano Pereira (FC Porto), Gaston Silva (Independiente), Martin Caceres (Lazio), Guillermo Varela (Penarol)
Midfielders: Nahitan Nandez (Boca Juniors), Lucas Torreira (Sampdoria), Matias Vecino (Inter Milan), Federico Valverde (Real Madrid), Rodrigo Bentancur (Juventus), Carlos Sanchez (Monterrey), Giorgian De Arrascaeta (Cruzeiro), Diego Laxalt (Genoa), Cristian Rodriguez (Penarol), Jonathan Urretaviscaya (Monterrey), Nicolas Lodeiro (Seattle Sounders), Gaston Ramirez (Sampdoria)
Forwards: Cristhian Stuani (Girona), Maximiliano Gomez (Celta Vigo), Edinson Cavani (PSG), Luis Suarez (Barcelona)