Guinea's hopes of reaching a maiden World Cup are in tatters after Hamdou Elhouni's strike secured victory for ten-man Libya in Monastir.
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The Libyans almost staged a remarkable comeback after two late points before Alkhali Bangoura's late winner.
"Mr. Trump is the president of the United States of America and as such of course [I have] huge respect for what he does," Infantino said.
Tunisia won their second game to open their World Cup qualifying group campaign with a 1-0 win over Libya in neutral territory in Algeria on Friday.
Ivory Coast top Group C in their third-round World Cup qualifying campaign after coming from behind to win 3-1 at home to Mali.
Three of the five African teams at the 2014 World Cup have been drawn in the same group to qualify for the 2018 edition.
Cameroon qualified for the 2017 African Nations Cup with a 1-0 win over Mauritania on Friday.
Mustapha Yatabare scored in the 89th minute to give Mali a 1-0 win at Equatorial Guinea in African Nations Cup qualifying on Monday.
Zambia were held to a 1-1 draw by Congo in a key African Nations Cup qualifier on Wednesday.
Nigeria advanced to the third round of African qualifying for the 2018 World Cup with a 2-0 win over Swaziland on Tuesday.
African giants Senegal and Ghana were both held to draws away from home as their 2018 World Cup qualifying campaigns got off to a shaky start.
Morocco beat Libya 1-0 as the 2017 African Nations Cup qualifiers got underway on Friday, while Swaziland defeated Guinea 2-1.
Radamel Falcao lifted Colombia to a 1-0 win over Costa Rica in a friendly on Saturday as his team tunes up for the Copa America.
Gabon will host the 2017 African Nations Cup in place of war-torn Libya.
The president of the national football federation says Ethiopia will bid to host the 2017 African Cup of Nations after Libya pulled out citing security concerns.