A late goal from Lucas Ocampos secured Marseille a 1-0 win at Nantes to maintain their 100 percent start two games into the new Ligue 1 campaign.
Rudi Garcia's men had seen an effort from Florian Thauvin ruled out for offside before Maxime Lopez sent an effort just wide.
The visitors, though, made sure they left La Beaujoire-Louis-Fonteneau with all three points when Argentine midfielder Ocampos slotted in a rebound with just two minutes left.
However, there was still time left for Nantes striker Emiliano Sala to head a late chance only just off target as Claudio Ranieri's side were left to reflect on a second straight Ligue 1 defeat.
Ranieri was forced to make his three substitutions within the first 24 minutes as skipper Valentin Rongier hurt an elbow after just 12 minutes, Yacine Bammou followed eight minutes later with a thigh injury, and Alexander Kacaniklic injured a leg.
Marseille must now regroup ahead of Thursday's Europa League playoff against Slovenian side NK Domzale, when they will be looking to stretch an unbeaten run which currently stands at 21 matches.
St Etienne also moved onto six points from two games after a 1-0 win at Caen, with Romain Hamouma scoring the only goal.
Hamouma netted the crucial strike on 67 minutes when he latched onto a through-ball and raced clear down the left before slotting his shot under the goalkeeper to leave Caen still pointless.
Marseille and St Etienne are level on points atop the table with Lyon, who beat Rennes on Friday night.
Jimmy Durmaz's 43rd-minute penalty gave Toulouse their first win of the season, 1-0 at Montpelier, who had beaten Caen a week ago.
Angers, who drew 2-2 with Bordeaux last week, also secured a win away from home, beating Amiens 2-0 with goals from Enzo Crivelli and Thomas Mangani.
Crivelli clipped home a neat finish on 27 minutes after being played into the right side of the penalty area by Mangani, who got on the scoresheet himself early in the second half when, on 56 minutes, he lobbed the ball back over Amiens goalkeeper Regis Gurtner who had been stranded after rushing out to make a sliding challenge on Crivelli as the striker chased down a long ball.
Meanwhile, Valentin Vada and Younousse Sankhare struck to keep Bordeaux unbeaten with a 2-0 home win over Metz.
The hosts, who drew their first domestic match having failed to progress in the Europa League qualifiers, took the lead just before half-time through Vada, who produced a neat turn at the edge of the penalty area and a low shot inside the near post.
Senegal midfielder Younousse Sankhare added a second in the 64th minute when he swept in from close range after Brazil forward Malcom cut in from the right and clipped the ball across the six-yard box.