Who will win when No. 12 Syracuse meets No. 3 Notre Dame at Yankee Stadium? Our reporters pick that game, plus No. 9 West Virginia at Oklahoma State, No. 16 Iowa State at No. 15 Texas and No. 24 Cincinnati at No. 11 UCF.
ESPN reporters pick Week 12's biggest games
Notre Dame looking for more balanced offense with Book back (2:24)
Kirk Herbstreit breaks down the matchups he likes this week, including No. 12 Syracuse vs. No. 3 Notre Dame as Ian Book makes his return. (2:24)