Week 10 in the NFL is not a week for close games. As of Wednesday night, every single game on the schedule had a line of at least three points. That means every game this week is eligible to be chosen as our Upset Watch for the week. But for the game that we think is the most likely upset, you have to wait all the way to the end, when Monday Night Football airs on ESPN.
Lines courtesy of the Westgate Las Vegas SuperBook, as of Thursday morning.
Upset watch: New York Giants at San Francisco 49ers (-3)
Nationally televised games can do a lot